The brain has been the last “terra incognita” of the body for medical exploration, largely because its matter is so different from that of the rest of the body. In 1986 the eminent evolutionary biologist John Maynard Smith identified the problem of how the brain works as one of the two outstanding problems in biology (along with how a simple egg develops into a complex adult organism). Most of us have experienced some apparently inexplicable quirk of the mind, such as selective memory loss. Without obvious “hard wiring”, anatomical “labels” or other guiding features, medical scientists have struggled to identify its parts, their functions and connections to the mind. Not that this has stopped curiosity; there is anthropological evidence dating back some thousands of years for crude but sometimes successful attempts to open the skull and get at the brain. Rita Carter is an award-winning medical writer. (Medical Journalists’ Association prize for outstanding contribution). In Mapping the Mind she explores the l